Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4182979 | 0.85 | MAPK1 (0.57) | TP53KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL9512641 | 0.79 | POLB (0.62) | GRM2MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL3177594 | 0.78 | GRM2 (0.60) | GRM2NPC1RAB9ATP53KDM4E | |
| SCHEMBL9514131 | 0.76 | ALDH1A1 (0.60) | GRM2NPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9742828 | 0.76 | ALDH1A1 (0.52) | KDM4EALDH1A1SMN1; SMN2FAAHHTT | |
| SCHEMBL1143656 | 0.75 | NPC1 (0.85) | NPC1RAB9ATP53KDM4EMEN1 | |
| SCHEMBL9511632 | 0.73 | HTT (0.59) | TP53KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL28958322 | 0.73 | ALDH1A1 (0.50) | GRM2NPC1KDM4EALDH1A1KMT2A | |
| SCHEMBL9743824 | 0.73 | ALDH1A1 (0.44) | NPC1MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL31484892 | 0.72 | HRH3 (0.78) | NPC1RAB9ATP53KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169859-A | Antisecretory or antiulcer agents | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1992-12-08 | — | — | US | disclosed |
| EP-0455774-A1 | THIAZOLIDINONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1991-11-13 | — | — | EP | disclosed |
| WO-1991008203-A1 | NOVEL THIAZOLIDINONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1991-06-13 | — | — | WO | disclosed |