Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | RECQL | P46063 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2939822 | 0.86 | ALDH1A1 (0.45) | ALDH1A1KDM4EMAPTTDP1RECQL | |
| SCHEMBL7637942 | 0.82 | TRPA1 (0.59) | ALDH1A1KDM4EMAPTTDP1RECQL | |
| SCHEMBL11552812 | 0.79 | ACHE (0.45) | ALDH1A1KDM4EMAPTTDP1CYP3A4 | |
| SCHEMBL9743119 | 0.79 | TRPA1 (0.50) | ALDH1A1KDM4EMAPTTDP1RECQL | |
| SCHEMBL9744550 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPTTDP1CYP3A4 | |
| SCHEMBL11785835 | 0.77 | PDK2 (0.45) | ALDH1A1KDM4EMAPTTDP1RECQL | |
| SCHEMBL11024469 | 0.77 | TRPA1 (0.59) | ALDH1A1KDM4EMAPTTDP1RECQL | |
| SCHEMBL28696280 | 0.77 | ALDH1A1 (0.45) | ALDH1A1KDM4EMAPTTDP1RECQL | |
| SCHEMBL28077328 | 0.76 | CNR2 (0.48) | ALDH1A1KDM4EMAPTTDP1RECQL | |
| SCHEMBL7642852 | 0.76 | TDP1 (0.52) | ALDH1A1KDM4EMAPTTDP1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5087548-A | POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION | JAPAN SYNTHETIC RUBBER CO., INC. (JP) | 1992-02-11 | — | — | US | disclosed |