Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | AKR1B10 | O60218 | 5/20 | 0.72 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.72 |
| ▸ | CA12 | O43570 | 3/20 | 0.72 |
| ▸ | CA7 | P43166 | 3/20 | 0.72 |
| ▸ | CA9 | Q16790 | 3/20 | 0.72 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.72 |
| ▸ | CA4 | P22748 | 2/20 | 0.72 |
| ▸ | CA6 | P23280 | 2/20 | 0.72 |
| ▸ | CA5A | P35218 | 2/20 | 0.72 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.72 |
| ▸ | TTR | P02766 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9743395 | 1.00 | LMNA (0.73) | LMNAAKR1B10AKR1B1CA12CA7 | |
| SCHEMBL13552179 | 0.88 | LMNA (0.93) | LMNAAKR1B10AKR1B1CA12CA7 | |
| Benzyl Cinnamate SCHEMBL1871854 | 0.85 | LMNA (1.00) | LMNAAKR1B10AKR1B1CA12CA7 | |
| Benzyl Cinnamate SCHEMBL43212 | 0.85 | LMNA (1.00) | LMNAAKR1B10AKR1B1CA12CA7 | |
| Benzyl Cinnamate SCHEMBL43213 | 0.85 | LMNA (1.00) | LMNAAKR1B10AKR1B1CA12CA7 | |
| Benzyl Cinnamate SCHEMBL901152 | 0.85 | LMNA (1.00) | LMNAAKR1B10AKR1B1CA12CA7 | |
| SCHEMBL10074238 | 0.84 | LMNA (0.79) | LMNAAKR1B10AKR1B1CA12CA7 | |
| SCHEMBL14192951 | 0.84 | LMNA (0.79) | LMNAAKR1B10AKR1B1CA12CA7 | |
| SCHEMBL28388377 | 0.84 | LMNA (0.79) | LMNAAKR1B10AKR1B1CA12CA7 | |
| SCHEMBL4501585 | 0.84 | AKR1B10 (1.00) | LMNAAKR1B10AKR1B1CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128448-A | Peptide hormones | HOFFMAN-LA ROCHE INC. (US) | 1992-07-07 | — | — | US | disclosed |