Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.68 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744032 | 0.91 | TMEM97 (0.56) | TMEM97ALDH1A1MAPTLMNANPSR1 | |
| SCHEMBL9743903 | 0.88 | TMEM97 (0.86) | TMEM97ALOX5ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL9742816 | 0.86 | TMEM97 (0.50) | TMEM97ALDH1A1SMN1; SMN2USP2HPGD | |
| SCHEMBL9744708 | 0.83 | ALOX5 (0.51) | TMEM97ALOX5ALDH1A1LMNANPSR1 | |
| SCHEMBL9744829 | 0.82 | ALDH1A1 (0.58) | TMEM97ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL9216935 | 0.80 | TMEM97 (0.44) | TMEM97ALDH1A1MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL9214919 | 0.80 | USP2 (0.47) | TMEM97ALDH1A1LMNANPSR1USP2 | |
| SCHEMBL24366776 | 0.79 | DRD3 (0.54) | TMEM97MEN1KMT2A | |
| SCHEMBL30469759 | 0.79 | DRD3 (0.54) | TMEM97MEN1KMT2A | |
| SCHEMBL81654 | 0.79 | ALDH1A1 (0.67) | TMEM97ALOX5ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171746-A | THIAZOLE AND IMIDAZOLE DERIVATIVES AND ANTIULCER COMPOSITION CONTAINING SAME | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0452076-A1 | Thiazole and imidazole derivatives and antiulcer composition containing same | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1991-10-16 | — | — | EP | disclosed |