Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RAC1 | P63000 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9742816 | 0.85 | TMEM97 (0.50) | TMEM97USP2ALDH1A1MAPK1HSD17B10 | |
| SCHEMBL9743754 | 0.83 | TMEM97 (0.68) | ALOX5TMEM97USP2MEN1KMT2A | |
| SCHEMBL9744829 | 0.79 | ALDH1A1 (0.58) | TMEM97USP2KMT2AALDH1A1LMNA | |
| SCHEMBL9393819 | 0.78 | ALOX5 (0.61) | ALOX5TMEM97MEN1KMT2AALDH1A1 | |
| SCHEMBL9214919 | 0.77 | USP2 (0.47) | TMEM97USP2ALDH1A1LMNAMAPK1 | |
| SCHEMBL9743459 | 0.76 | ABL1 (0.39) | USP2ALDH1A1LMNARAB9AABL1 | |
| SCHEMBL9744032 | 0.76 | TMEM97 (0.56) | TMEM97USP2MEN1KMT2AALDH1A1 | |
| SCHEMBL9443101 | 0.73 | ALOX5 (0.64) | ALOX5MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL9186874 | 0.72 | ALOX5 (0.57) | ALOX5TMEM97MEN1KMT2AALDH1A1 | |
| SCHEMBL8128564 | 0.72 | ALOX5 (0.57) | ALOX5MEN1KMT2AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171746-A | THIAZOLE AND IMIDAZOLE DERIVATIVES AND ANTIULCER COMPOSITION CONTAINING SAME | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0452076-A1 | Thiazole and imidazole derivatives and antiulcer composition containing same | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1991-10-16 | — | — | EP | disclosed |