Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9742816 | 0.82 | TMEM97 (0.50) | ALDH1A1MAPK1SMN1; SMN2TMEM97GAA | |
| SCHEMBL9743754 | 0.82 | TMEM97 (0.68) | ALDH1A1MAPTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL9744708 | 0.79 | ALOX5 (0.51) | ALDH1A1LMNAKMT2AMAPK1TMEM97 | |
| SCHEMBL9743960 | 0.79 | ALDH1A1 (0.56) | ALDH1A1MAPTLMNAAHRKMT2A | |
| SCHEMBL9214919 | 0.76 | USP2 (0.47) | ALDH1A1LMNAMAPK1TMEM97GAA | |
| SCHEMBL9744032 | 0.75 | TMEM97 (0.56) | ALDH1A1MAPTLMNAKMT2ATMEM97 | |
| SCHEMBL9476341 | 0.75 | ALDH1A1 (0.57) | ALDH1A1MAPTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL8133629 | 0.73 | MAPT (0.55) | ALDH1A1MAPTLMNAKMT2AMAPK1 | |
| SCHEMBL2708797 | 0.72 | PDK1 (0.60) | ALDH1A1MAPTKMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL521706 | 0.71 | MAPT (0.54) | ALDH1A1MAPTLMNAAHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171746-A | THIAZOLE AND IMIDAZOLE DERIVATIVES AND ANTIULCER COMPOSITION CONTAINING SAME | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0452076-A1 | Thiazole and imidazole derivatives and antiulcer composition containing same | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1991-10-16 | — | — | EP | disclosed |