Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.46 |
| ▸ | QDPR | P09417 | 3/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL339008 | 0.87 | TP53 (0.43) | APPTP53TDP1CSNK2A2CSNK2B | |
| SCHEMBL31299941 | 0.85 | TP53 (0.41) | APPTP53TDP1CSNK2A2CSNK2B | |
| SCHEMBL9721271 | 0.78 | APP (0.48) | APPTRPA1ALOX5QDPRSNCA | |
| SCHEMBL12036579 | 0.77 | HSD17B1 (0.36) | APPTRPA1TP53TDP1CSNK2A2 | |
| SCHEMBL2846017 | 0.77 | SENP1 (0.54) | CSNK2A2CSNK2BCSNK2A1ALDH1A1POLB | |
| SCHEMBL9743439 | 0.77 | SELL (0.59) | TP53TDP1KDM4EALDH1A1POLB | |
| SCHEMBL12036570 | 0.76 | TP53 (0.38) | TP53TDP1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6382158 | 0.76 | ALDH1A1 (0.40) | TP53TDP1ALDH1A1MAPT | |
| SCHEMBL28696279 | 0.76 | SENP1 (0.52) | CSNK2A2CSNK2BCSNK2A1ALOX5ESR2 | |
| SCHEMBL14451020 | 0.75 | ESR2 (0.61) | ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5087548-A | POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION | JAPAN SYNTHETIC RUBBER CO., INC. (JP) | 1992-02-11 | — | — | US | disclosed |
| EP-0227487-A2 | Positive type radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1987-07-01 | — | — | EP | disclosed |