Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9745731 | 0.96 | ALDH1A1 (0.57) | DRD3KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL8497966 | 0.87 | DRD3 (0.56) | DRD3KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL9548110 | 0.87 | DRD3 (0.49) | DRD3KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL9744130 | 0.85 | KDM4E (0.56) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9744140 | 0.85 | KDM4E (0.56) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9744839 | 0.84 | L3MBTL1 (0.52) | DRD3KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL9743994 | 0.84 | L3MBTL1 (0.54) | DRD3KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL22014785 | 0.83 | KDM4E (0.55) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL9744163 | 0.83 | DRD3 (0.44) | DRD3KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL9743438 | 0.83 | L3MBTL1 (0.53) | DRD3KDM4EALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147871-A | Anti-bacterial cephalosporin compounds | HOFFMANN LA-ROCHE, INC. (US) | 1992-09-15 | — | — | US | claimed |