Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27783377 | 0.86 | HSD11B1 (0.64) | HSD11B1 | |
| SCHEMBL3455510 | 0.79 | GRM5 (0.58) | HSD11B1FAAHKMT2AMEN1GAA | |
| SCHEMBL31583752 | 0.79 | P2RX7 (0.58) | HSD11B1SMN1; SMN2LMNAALDH1A1NPC1 | |
| SCHEMBL1968849 | 0.78 | HSD11B1 (0.49) | HSD11B1SMN1; SMN2LMNAFAAHALDH1A1 | |
| SCHEMBL20792326 | 0.76 | FAAH (0.43) | HSD11B1LMNAFAAHALDH1A1HTT | |
| SCHEMBL14082154 | 0.76 | TRPV1 (0.51) | HSD11B1FAAHHTTKMT2A | |
| SCHEMBL3165964 | 0.75 | ALDH1A1 (0.68) | HSD11B1SMN1; SMN2LMNAALDH1A1HTT | |
| SCHEMBL7691441 | 0.75 | EGLN1 (0.56) | HSD11B1ALDH1A1 | |
| SCHEMBL1012465 | 0.74 | HTT (0.50) | HSD11B1SMN1; SMN2LMNAFAAHALDH1A1 | |
| SCHEMBL1675968 | 0.74 | KMT2A (0.57) | HSD11B1FAAHALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153212-A | For human or veterinary use | CENTRE INTERNATIONAL DE RECHERCHES DERMATOGLOGIQUES (C.I.R.D.) (FR) | 1992-10-06 | — | — | US | disclosed |