Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | DHFR | P00374 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL447549 | 1.00 | SIGMAR1 (0.47) | SIGMAR1LMNALTA4HTSHRDHFR | |
| Bromide SCHEMBL28805308 | 0.98 | SIGMAR1 (0.46) | SIGMAR1LMNALTA4HTSHRDHFR | |
| SCHEMBL2982806 | 0.98 | TSHR (0.46) | SIGMAR1LMNALTA4HTSHRDHFR | |
| Hydrochloric Acid SCHEMBL2978407 | 0.96 | LMNA (0.46) | SIGMAR1LMNALTA4HTSHRDHFR | |
| SCHEMBL15094370 | 0.94 | TSHR (0.46) | SIGMAR1LTA4HTSHRDHFRSLC6A3 | |
| SCHEMBL6620777 | 0.86 | HRH3 (0.53) | LTA4HHRH3 | |
| SCHEMBL10382845 | 0.81 | ALDH1A1 (0.41) | TSHRDHFRRAB9ANPC1 | |
| SCHEMBL28598923 | 0.80 | TSHR (0.50) | SIGMAR1LMNATSHRSLC6A3 | |
| SCHEMBL23279497 | 0.80 | KMT2A (0.53) | SIGMAR1LMNALTA4HTSHRHPGD | |
| SCHEMBL20892082 | 0.80 | MC4R (0.53) | SIGMAR1LTA4HTSHRHRH3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |