Acetone

Acetone

SCHEMBL9744462

CC(C)=O.CC(C)=O.OC[C@H](O)C=C[C@@H](O)CO

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.48
LMNA P02545 3/20 0.35
ALDH1A1 P00352 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
OR51E2 Q9H255 1/20 0.35
GAPDH P04406 1/20 0.33
MAPT P10636 2/20 0.32
USP2 O75604 1/20 0.32
CYP3A4 P08684 1/20 0.32
RECQL P46063 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TGFBR1 P36897 1/20 0.32
TP53 P04637 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
MAPK1 P28482 1/20 0.31
CYP2C19 P33261 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8014456 0.84 AKR1B1 (0.53) AKR1B1LMNAALDH1A1TDP1OR51E2
SCHEMBL8014451 0.84 AKR1B1 (0.53) AKR1B1LMNAALDH1A1TDP1OR51E2
Acetone SCHEMBL2871076 0.80 AKR1B1 (0.78) AKR1B1LMNAALDH1A1TDP1OR51E2
Acetone SCHEMBL5567209 0.80 AKR1B1 (0.78) AKR1B1LMNAALDH1A1TDP1OR51E2
Acetone SCHEMBL1711073 0.80 AKR1B1 (0.78) AKR1B1LMNAALDH1A1TDP1OR51E2
Acetone SCHEMBL28376337 0.80 AKR1B1 (0.78) AKR1B1LMNAALDH1A1TDP1OR51E2
Acetone SCHEMBL9466071 0.80 AKR1B1 (0.78) AKR1B1LMNAALDH1A1TDP1OR51E2
SCHEMBL12927523 0.77 GAPDH (0.50) AKR1B1LMNAALDH1A1TDP1GAPDH
SCHEMBL18315417 0.76 OR51E2 (0.42) AKR1B1OR51E2USP2TGFBR1CYP2C9
SCHEMBL18315416 0.76 OR51E2 (0.42) AKR1B1OR51E2USP2TGFBR1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5164113-A Ferroelectric, polarization promoters MITSUBISHI RAYON CO., LTD. (JP) 1992-11-17 US disclosed
EP-0396410-A2 Optical active compound and liquid crystal composition MITSUBISHI RAYON CO., LTD. (JP) 1990-11-07 EP disclosed