Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9746266 | 0.81 | CASR (0.46) | HSP90AA1HSP90AB1RAB9AUSP2CYP2A13 | |
| SCHEMBL9206848 | 0.77 | PDK1 (0.50) | RAB9AUSP2PDE10AALDH1A1HSD17B10 | |
| SCHEMBL9743754 | 0.76 | TMEM97 (0.68) | ALOX5RAB9AUSP2ALDH1A1HSD17B10 | |
| SCHEMBL9744032 | 0.76 | TMEM97 (0.56) | USP2ALDH1A1TP53MAPTGAA | |
| SCHEMBL9744020 | 0.75 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1USP2CYP2A13ALDH1A1 | |
| SCHEMBL9216935 | 0.73 | TMEM97 (0.44) | HSP90AA1RAB9AUSP2ALDH1A1MAPK1 | |
| SCHEMBL5133332 | 0.73 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1 | |
| SCHEMBL9214919 | 0.72 | USP2 (0.47) | RAB9AUSP2ALDH1A1HSD17B10MAPK1 | |
| SCHEMBL9742816 | 0.71 | TMEM97 (0.50) | RAB9AUSP2ALDH1A1HSD17B10MAPK1 | |
| Fopirtoline SCHEMBL287363 | 0.70 | RAB9A (0.49) | HSP90AA1RAB9APDE10ACYP2A13ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171746-A | THIAZOLE AND IMIDAZOLE DERIVATIVES AND ANTIULCER COMPOSITION CONTAINING SAME | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0452076-A1 | Thiazole and imidazole derivatives and antiulcer composition containing same | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1991-10-16 | — | — | EP | disclosed |