Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744730 | 0.81 | HSP90AA1 (0.56) | USP2RAB9AMAPTCYP2A13HSP90AA1 | |
| SCHEMBL25212157 | 0.79 | HPGD (0.63) | CASRRAB9AMAPTNPC1LMNA | |
| SCHEMBL9743754 | 0.76 | TMEM97 (0.68) | USP2RAB9AMAPTNPC1LMNA | |
| SCHEMBL9744032 | 0.76 | TMEM97 (0.56) | CASRUSP2MAPTLMNAHPGD | |
| SCHEMBL9743877 | 0.75 | CASR (0.45) | CASRUSP2IDO1RAB9AMAPT | |
| SCHEMBL9214919 | 0.72 | USP2 (0.47) | USP2RAB9ALMNAHPGDALDH1A1 | |
| SCHEMBL10816690 | 0.72 | LMNA (0.51) | RAB9AMAPTNPC1LMNAHPGD | |
| SCHEMBL9742816 | 0.71 | TMEM97 (0.50) | USP2RAB9ANPC1HPGDSMN1; SMN2 | |
| SCHEMBL7622009 | 0.71 | PSMB8 (0.51) | IDO1RAB9AMAPTNPC1LMNA | |
| Fopirtoline SCHEMBL287363 | 0.70 | RAB9A (0.49) | RAB9AMAPTNPC1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171746-A | THIAZOLE AND IMIDAZOLE DERIVATIVES AND ANTIULCER COMPOSITION CONTAINING SAME | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0452076-A1 | Thiazole and imidazole derivatives and antiulcer composition containing same | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1991-10-16 | — | — | EP | disclosed |