Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CHRNA7 | P36544 | 8/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27330300 | 0.91 | PTGS2 (0.55) | PTGS2PTGS1CA9CHRNA7 | |
| SCHEMBL9200880 | 0.87 | PTGS2 (0.63) | PTGS2PTGS1CA9CHRNA7SMN1; SMN2 | |
| SCHEMBL9204576 | 0.87 | PTGS2 (0.59) | PTGS2PTGS1CHRNA7SMN1; SMN2 | |
| SCHEMBL9199556 | 0.86 | AOC3 (0.65) | PTGS2PTGS1CHRNA7 | |
| SCHEMBL9209551 | 0.86 | ALOX5 (0.60) | PTGS2CA9CHRNA7 | |
| SCHEMBL8925594 | 0.85 | RARG (0.60) | PTGS2CHRNA7SMN1; SMN2 | |
| SCHEMBL8925566 | 0.85 | CHRNA7 (0.57) | PTGS2CHRNA7SMN1; SMN2 | |
| SCHEMBL9208261 | 0.85 | CHRNA7 (0.51) | PTGS2CHRNA7SMN1; SMN2 | |
| SCHEMBL9210999 | 0.84 | PTGS2 (0.55) | PTGS2PTGS1CA9CHRNA7SMN1; SMN2 | |
| SCHEMBL9199063 | 0.84 | CHRNA7 (0.66) | PTGS2PTGS1CA9CHRNA7SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134142-A | PYRAZOLE DERIVATIVES, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-28 | — | — | US | disclosed |