Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanidine SCHEMBL9332820 | 1.00 | — | — | |
| SCHEMBL179970 | 0.81 | — | — | |
| Ethylene Glycol SCHEMBL11369374 | 0.76 | — | — | |
| Guanidine SCHEMBL1317565 | 0.74 | NOS1 (0.32) | — | |
| Guanidine SCHEMBL9716572 | 0.74 | NOS1 (0.32) | — | |
| Bicarbonate SCHEMBL1304077 | 0.72 | ALDH1A1 (0.36) | — | |
| Phosphoric Acid SCHEMBL11158359 | 0.70 | LMNA (0.38) | — | |
| SCHEMBL11192857 | 0.68 | ALDH1A1 (0.50) | — | |
| Guanidine SCHEMBL1318808 | 0.68 | ALDH1A1 (0.33) | — | |
| SCHEMBL8573726 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5087384-A | Containing urea, thiourea, biuret, or alkyl substituted urea or thiourea | CHEMIE LINZ GESELLSCHAFT M.B.H. (AT) | 1992-02-11 | — | — | US | claimed |
| US-5087384-A | Containing urea, thiourea, biuret, or alkyl substituted urea or thiourea | CHEMIE LINZ GESELLSCHAFT M.B.H. (AT) | 1992-02-11 | — | — | US | disclosed |