Quinoline

Quinoline

SCHEMBL6568759

c1ccc2ncccc2c1.c1cnccn1

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.85
NPC1 O15118 3/20 0.52
RAB9A P51151 2/20 0.52
POLB P06746 1/20 0.52
CYP3A4 P08684 4/20 0.50
PDGFRB P09619 1/20 0.48
PDGFRA P16234 1/20 0.48
HTT P42858 3/20 0.48
KDM4E B2RXH2 3/20 0.48
MAPT P10636 3/20 0.48
CASP1 P29466 2/20 0.48
CYP1A2 P05177 2/20 0.48
CYP2C19 P33261 2/20 0.48
TP53 P04637 2/20 0.48
HSP90AA1 P07900 2/20 0.48
TSHR P16473 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
MEN1 O00255 1/20 0.48
CASP7 P55210 1/20 0.48
KMT2A Q03164 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinoline SCHEMBL28077521 1.00 ALDH1A1 (0.85) ALDH1A1NPC1RAB9APOLBCYP3A4
Quinoline SCHEMBL2774 0.92 ALDH1A1 (1.00) ALDH1A1NPC1RAB9APOLBCYP3A4
Quinoline SCHEMBL29822171 0.92 ALDH1A1 (1.00) ALDH1A1NPC1RAB9APOLBCYP3A4
Quinoline SCHEMBL29349552 0.92 ALDH1A1 (1.00) ALDH1A1NPC1RAB9APOLBCYP3A4
Quinoline SCHEMBL32661377 0.92 ALDH1A1 (1.00) ALDH1A1NPC1RAB9APOLBCYP3A4
Quinoline SCHEMBL1270969 0.92 ALDH1A1 (1.00) ALDH1A1NPC1RAB9APOLBCYP3A4
Quinoline SCHEMBL1608752 0.91 ALDH1A1 (0.77) ALDH1A1NPC1RAB9APOLBCYP3A4
Quinoline SCHEMBL23202414 0.90 ALDH1A1 (0.94) ALDH1A1NPC1RAB9APOLBCYP3A4
Quinoline SCHEMBL6381814 0.90 ALDH1A1 (0.94) ALDH1A1NPC1RAB9APOLBCYP3A4
Quinoline SCHEMBL4955314 0.90 ALDH1A1 (0.94) ALDH1A1NPC1RAB9APOLBCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113388105-B Polyquinolinazine compound and preparation method and application thereof 香港科技大学深圳研究院 2022-09-20 CN claimed
CN-113388105-A Polyquinolinazine compound and preparation method and application thereof 香港科技大学深圳研究院 2021-09-14 CN claimed
CN-110372710-A Material of main part for el light emitting device 环球展览公司 2019-10-25 CN claimed
CN-102378985-A Encapsulated radio frequency identification tag and method of making same SABIC INNOVATIVE PLASTICS IP 2012-03-14 CN claimed
WO-2004073394-A2 CHEMICAL COMPOSITE ATTRACTANT OF PREMOLTING FEMALE BLUE CRABS EAST CAROLINA UNIVERSITY (US) 2004-09-02 WO claimed
US-20230397497-A1 NIR-ABSORBING MATERIALS FOR OPTOELECTRONIC APPLICATIONS UNIVERSITY OF SOUTHERN CALIFORNIA 2023-12-07 US disclosed
CN-113388105-B Polyquinolinazine compound and preparation method and application thereof 香港科技大学深圳研究院 2022-09-20 CN disclosed
CN-113388105-A Polyquinolinazine compound and preparation method and application thereof 香港科技大学深圳研究院 2021-09-14 CN disclosed
CN-105452398-B Composition for ink, ink jet recording method and tingle body using this composition for ink 日本化药株式会社 2018-07-10 CN disclosed
CN-108232208-A Method for the mixed catalyst of fuel cell and for manufacturing it 现代自动车株式会社 2018-06-29 CN disclosed
CN-108137565-A Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device 株式会社半导体能源研究所 2018-06-08 CN disclosed
CN-107250254-A The acrylonitrile butadient styrene of high-modulus height flowing talcum filling with enhanced surface aesthetic 沙特基础工业全球技术公司 2017-10-13 CN disclosed
CN-102378985-A Encapsulated radio frequency identification tag and method of making same SABIC INNOVATIVE PLASTICS IP 2012-03-14 CN disclosed
CN-101282931-A Tanaka Hiroaki TOYO INK MFG CO (JP) 2008-10-08 CN disclosed
CN-1875664-A Barrier film for light-emitting display device and method for manufacturing same IDEMITSU KOSAN CO (JP) 2006-12-06 CN disclosed
CN-1530140-A Vermis expelling resinate and its preparation ������������� 2004-09-22 CN disclosed
US-20040180034-A1 Anthelmintic resinates and a method for their preparation HUGHES LYN (US) 2004-09-16 US disclosed
EP-1457213-A1 Anthelmintic resinates and a method for their preparation ROHM AND HAAS COMPANY (US) 2004-09-15 EP disclosed
WO-2004073394-A2 CHEMICAL COMPOSITE ATTRACTANT OF PREMOLTING FEMALE BLUE CRABS EAST CAROLINA UNIVERSITY (US) 2004-09-02 WO disclosed
EP-0695740-A1 Quinonediazine sulfonic acid esters and positive photoresist compositions comprising the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-02-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230397497-A1 NIR-ABSORBING MATERIALS FOR OPTOELECTRONIC APPLICATIONS CRY2, CRYAA, CRY1 ALDH1A1 168/4885NPC1 643/4885RAB9A 3053/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.