Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | SNCA | P37840 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6908269 | 0.86 | KMT2A (0.63) | RAB9AKMT2AMEN1TTRPOLB | |
| SCHEMBL6908272 | 0.86 | KMT2A (0.63) | RAB9AKMT2AMEN1TTRPOLB | |
| SCHEMBL27790551 | 0.81 | MAPT (0.56) | RAB9AKMT2AMEN1MAPTBACE1 | |
| SCHEMBL19543189 | 0.80 | MAPT (0.59) | RAB9AKMT2AMEN1TTRPOLB | |
| SCHEMBL3794210 | 0.80 | MEN1 (0.56) | RAB9AKMT2AMEN1TTRPOLB | |
| SCHEMBL9744534 | 0.79 | MAOB (0.57) | RAB9AKMT2AMEN1POLBMAPT | |
| SCHEMBL28003594 | 0.78 | EPHX2 (0.60) | RAB9AKMT2AMEN1POLBMAPT | |
| SCHEMBL11973532 | 0.77 | RAB9A (0.53) | RAB9AKMT2AMEN1TTRPOLB | |
| SCHEMBL648890 | 0.77 | KMT2A (0.60) | RAB9AKMT2AMEN1POLBMAPT | |
| SCHEMBL11973525 | 0.77 | RAB9A (0.53) | RAB9AKMT2AMEN1TTRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5164515-A | Chemical compounds | WENDSTONE CHEMICALS PLC (GB) | 1992-11-17 | — | — | US | disclosed |
| EP-0239354-A2 | 2,2-Dinitrophenylethane derivatives and their application as protecting compounds | Wendstone Chemicals P.L.C. (GB) | 1987-09-30 | — | — | EP | disclosed |