Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | TNKS | O95271 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL765933 | 0.83 | HCAR2 (0.59) | MAPTPTGS2HDAC3TNKSHDAC4 | |
| SCHEMBL309763 | 0.83 | HCAR2 (0.59) | MAPTPTGS2HDAC3TNKSHDAC4 | |
| Bicarbonate SCHEMBL867321 | 0.82 | HCAR2 (0.57) | MAPTPTGS2HDAC3TNKSHDAC4 | |
| Hydrochloric Acid SCHEMBL11763321 | 0.82 | HCAR2 (0.57) | MAPTPTGS2HDAC3TNKSHDAC4 | |
| SCHEMBL9745903 | 0.81 | RAB9A (0.48) | MAPTBACE1TDP1MEN1KMT2A | |
| SCHEMBL23512479 | 0.79 | KDM4E (0.57) | MAPTPTGS2HDAC3TNKSHDAC4 | |
| SCHEMBL7957010 | 0.79 | KDM4E (0.57) | MAPTPTGS2HDAC3TNKSHDAC4 | |
| SCHEMBL7957004 | 0.79 | KDM4E (0.57) | MAPTPTGS2HDAC3TNKSHDAC4 | |
| Ethylbenzene SCHEMBL27317767 | 0.78 | TP53 (0.58) | MAPTTDP1MEN1KMT2ANPC1 | |
| SCHEMBL2184446 | 0.77 | ALDH1A1 (0.60) | MAPTBACE1HDAC3TNKSHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101589038-A | Heterocyclidene-N-(aryl)acetamide derivative | MOCHIDA PHARM CO LTD (JP) | 2009-11-25 | — | — | CN | disclosed |