Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555470 | 0.85 | HTT (0.54) | HTTKMT2ASMN1; SMN2TSHRMAPT | |
| SCHEMBL1985055 | 0.82 | L3MBTL1 (0.60) | SMN1; SMN2TSHRALDH1A1PKMMAPK1 | |
| SCHEMBL9143135 | 0.82 | TSHR (0.78) | HTTKMT2ASMN1; SMN2TSHRMAPT | |
| SCHEMBL25788236 | 0.81 | TSHR (0.69) | TSHRMAPTUSP2ALDH1A1HSD17B10 | |
| SCHEMBL3040886 | 0.81 | LTA4H (0.55) | HTTKMT2ASMN1; SMN2TSHRMAPT | |
| SCHEMBL6634317 | 0.80 | KMT2A (0.50) | HTTKMT2ASMN1; SMN2TSHRMAPT | |
| SCHEMBL1496817 | 0.80 | NPSR1 (0.51) | HTTKMT2ASMN1; SMN2TSHRMAPT | |
| SCHEMBL28052256 | 0.80 | ALDH1A1 (0.50) | KMT2ATSHRMAPTALDH1A1HSD17B10 | |
| SCHEMBL23804499 | 0.79 | PKM (0.53) | SMN1; SMN2TSHRALDH1A1HSD17B10PKM | |
| SCHEMBL27697782 | 0.79 | NR4A2 (0.54) | HTTSMN1; SMN2TSHRUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5082587-A | ACHIRAL FLUORINE-CONTAINING LIQUID CRYSTALS | 3M INNOVATIVE PROPERTIES COMPANY | 1992-01-21 | — | — | US | disclosed |