Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.49 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | PAM | P19021 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9747014 | 1.00 | MAPT (0.49) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL18957607 | 0.86 | ALDH1A1 (0.44) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL31233086 | 0.86 | KDM4E (0.50) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL24805158 | 0.85 | MAPT (0.59) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9743045 | 0.85 | TRPA1 (0.48) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9743048 | 0.85 | TRPA1 (0.48) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL31233275 | 0.82 | MAPT (0.61) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL30383221 | 0.80 | MAPT (0.59) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL13099968 | 0.80 | ALDH1A1 (0.59) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL454263 | 0.79 | KDM4E (0.46) | MAPTMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200199058-A1 | SQUARYLIUM COMPOUNDS FOR USE IN DISPLAY DEVICES | NITTO DENKO CORPORATION (JP) | 2020-06-25 | — | — | US | disclosed |
| US-5087548-A | POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION | JAPAN SYNTHETIC RUBBER CO., INC. (JP) | 1992-02-11 | — | — | US | disclosed |
| EP-0227487-A2 | Positive type radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1987-07-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200199058-A1 | SQUARYLIUM COMPOUNDS FOR USE IN DISPLAY DEVICES | SQLE, FDFT1, ALDH1A2 | MAPT 3928/4885MEN1 3588/4885KMT2A 3169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.