Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.39 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | RARA | P10276 | 8/20 | 0.38 |
| ▸ | RARB | P10826 | 8/20 | 0.38 |
| ▸ | RARG | P13631 | 8/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 2/20 | 0.36 |
| ▸ | UGCG | Q16739 | 2/20 | 0.36 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9746653 | 0.87 | RARB (0.57) | CYP26A1CYP26B1RARARARBRARG | |
| SCHEMBL2095481 | 0.76 | RXRA (0.57) | CYP26A1CYP26B1PPARGRARARARB | |
| SCHEMBL9507898 | 0.74 | PPARG (0.50) | CYP26A1CYP26B1PPARGRARARARB | |
| SCHEMBL10834477 | 0.74 | RARB (0.59) | CYP26A1CYP26B1PPARGRARARARB | |
| SCHEMBL4668411 | 0.74 | CYP26B1 (0.52) | CYP26A1CYP26B1PPARGRARARARB | |
| SCHEMBL7142134 | 0.71 | CYP26B1 (0.49) | CYP26A1CYP26B1RARARARBRARG | |
| SCHEMBL17117601 | 0.71 | RXRA (0.48) | CYP26A1CYP26B1PPARGRARARARB | |
| SCHEMBL9746771 | 0.70 | RARA (0.51) | CYP26A1CYP26B1PPARGRARARARB | |
| SCHEMBL4365965 | 0.70 | CYP26B1 (0.55) | CYP26A1CYP26B1PPARGRARARARB | |
| SCHEMBL9746456 | 0.70 | RARA (0.63) | CYP26A1CYP26B1PPARGRARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220118-B1 | BICYCLIC NAPHTHALENIC DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN AND VETERINARY MEDICINE AND COSMETICS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1992-01-02 | — | — | EP | claimed |
| US-4826969-A | SKIN AND EYE DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. (FR) | 1989-05-02 | — | — | US | disclosed |