Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10063304 | 0.86 | MCHR1 (0.72) | MCHR1GAAL3MBTL1TDP1CYP2C9 | |
| SCHEMBL16135206 | 0.83 | MCHR1 (0.52) | MCHR1GAAL3MBTL1TDP1CYP2C9 | |
| SCHEMBL994418 | 0.81 | MCHR1 (0.73) | MCHR1GAATLR8RAB9ANPC1 | |
| SCHEMBL16511927 | 0.80 | MAPT (0.41) | MCHR1RAB9ANPC1MAPTMAPK1 | |
| SCHEMBL2520179 | 0.78 | LTA4H (0.50) | MCHR1GAAL3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL20696658 | 0.78 | MCHR1 (0.54) | MCHR1CYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL4273729 | 0.78 | RAB9A (0.56) | MCHR1CYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL16809050 | 0.77 | NPC1 (0.39) | MCHR1GAAL3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL4273391 | 0.77 | MAPT (0.59) | MCHR1GAAL3MBTL1TDP1CYP2C9 | |
| SCHEMBL27492328 | 0.76 | KCNA3 (0.44) | MCHR1CYP2C9CYP2C19CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4001194-A | — | — | None | — | — | JP | disclosed |
| JP-H041194-A | 1,10-PHENANTHROLINE DERIVATIVE | T HASEGAWA CO LTD | 1992-01-06 | — | — | JP | disclosed |