Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.47 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | FASN | P49327 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30905530 | 0.76 | NOS3 (0.53) | IMPDH2IMPDH1FASNGRIN2DGRIN3B | |
| SCHEMBL118018 | 0.76 | NOS3 (0.53) | IMPDH2IMPDH1FASNGRIN2DGRIN3B | |
| SCHEMBL28489960 | 0.73 | GRM5 (0.64) | IMPDH2IMPDH1CA1CA2CHEK1 | |
| SCHEMBL13037656 | 0.73 | CA2 (0.55) | IMPDH2IMPDH1CA1CA2CYP19A1 | |
| SCHEMBL1054605 | 0.73 | CA12 (0.56) | IMPDH2IMPDH1CA1CA2FASN | |
| SCHEMBL29891877 | 0.72 | IMPDH2 (0.51) | IMPDH2IMPDH1CA1CA2FASN | |
| Hydrochloric Acid SCHEMBL7004520 | 0.72 | GRM5 (0.62) | IMPDH2IMPDH1CA1CA2CHEK1 | |
| SCHEMBL9747072 | 0.72 | GRIN2D (0.63) | FASNGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL12310183 | 0.71 | CA2 (0.53) | IMPDH2IMPDH1CA1CA2CYP19A1 | |
| SCHEMBL12320904 | 0.71 | CA2 (0.53) | IMPDH2IMPDH1CA1CA2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511152-A2 | Quinoxaline compounds, their preparation and use | NOVO NORDISK A/S (DK) | 1992-10-28 | — | — | EP | disclosed |