Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.53 |
| ▸ | MMP1 | P03956 | 3/20 | 0.53 |
| ▸ | ANPEP | P15144 | 2/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9746636 | 0.77 | ANPEP (0.60) | MMP2MMP1ANPEPERAP2CA12 | |
| SCHEMBL16111997 | 0.77 | ANPEP (0.60) | MMP2MMP1ANPEPERAP2CA12 | |
| SCHEMBL11510848 | 0.76 | MEN1 (0.39) | PPARDKDM4EPOLBATML3MBTL1 | |
| SCHEMBL4144486 | 0.75 | MMP2 (0.51) | MMP2MMP1ANPEPERAP2CA12 | |
| SCHEMBL4144489 | 0.75 | MMP2 (0.51) | MMP2MMP1ANPEPERAP2CA12 | |
| SCHEMBL9683270 | 0.74 | MMP2 (0.53) | MMP2MMP1CA12CA1CA2 | |
| SCHEMBL7915207 | 0.73 | PPARD (0.44) | MMP2MMP1PPARDCA12CA1 | |
| SCHEMBL10842273 | 0.72 | MMP2 (0.51) | MMP2MMP1ANPEPERAP2CA12 | |
| SCHEMBL9311100 | 0.71 | ANPEP (0.46) | MMP2MMP1ANPEPERAP2KDM4E | |
| SCHEMBL9316059 | 0.71 | ANPEP (0.46) | MMP2MMP1ANPEPERAP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5099056-A | PROCESS FOR THE PRODUCTION OF N-SUBSTITUTED-AMINOMETHYLPHOSPHONIC ACID DIALKYLESTERS AND OF THE CORRESPONDING ACIDS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1992-03-24 | — | — | US | disclosed |