Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.50 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.47 |
| ▸ | EP300 | Q09472 | 1/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | FABP7 | O15540 | 1/20 | 0.45 |
| ▸ | FABP3 | P05413 | 1/20 | 0.45 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.45 |
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8784533 | 0.90 | CASP6 (0.59) | ALDH1A1CASP6HSD17B1HSD17B2PRMT3 | |
| SCHEMBL4480977 | 0.87 | CASP6 (0.50) | ALDH1A1CASP6HSD17B1HSD17B2PRMT3 | |
| SCHEMBL10390889 | 0.79 | ENPP2 (0.51) | ALDH1A1CASP6HSD17B1HSD17B2PRMT3 | |
| SCHEMBL4474391 | 0.79 | NSD2 (0.49) | ALDH1A1 | |
| SCHEMBL29963136 | 0.78 | HSD17B1 (0.76) | ALDH1A1CASP6HSD17B1HSD17B2CYP1A2 | |
| SCHEMBL19355161 | 0.78 | HSD17B1 (0.55) | ALDH1A1CASP6HSD17B1HSD17B2CYP1A2 | |
| SCHEMBL1122275 | 0.78 | HSD17B1 (0.76) | ALDH1A1CASP6HSD17B1HSD17B2CYP1A2 | |
| SCHEMBL11900180 | 0.78 | CASP6 (0.68) | ALDH1A1CASP6HSD17B1HSD17B2CYP1A2 | |
| SCHEMBL1807568 | 0.78 | HSD17B1 (0.55) | ALDH1A1CASP6HSD17B1HSD17B2CYP1A2 | |
| SCHEMBL8784680 | 0.78 | ENPP2 (0.50) | ALDH1A1CASP6HSD17B1HSD17B2PRMT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511152-A2 | Quinoxaline compounds, their preparation and use | NOVO NORDISK A/S (DK) | 1992-10-28 | — | — | EP | disclosed |