Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HK1 | P19367 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | CBX7 | O95931 | 3/20 | 0.43 |
| ▸ | CDYL2 | Q8N8U2 | 3/20 | 0.43 |
| ▸ | CDYL | Q9Y232 | 3/20 | 0.43 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744272 | 0.84 | ALDH1A1 (0.43) | ALDH1A1GAAPKMMEN1KMT2A | |
| SCHEMBL3456759 | 0.82 | KDM4E (0.62) | ALDH1A1MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL9744646 | 0.81 | LMNA (0.44) | ALDH1A1GAAPKMMEN1KMT2A | |
| SCHEMBL11999983 | 0.78 | KDM4E (0.54) | ALDH1A1GAAPKMMEN1KMT2A | |
| SCHEMBL14498505 | 0.76 | ALDH1A1 (0.46) | ALDH1A1GAAPKMMEN1KMT2A | |
| SCHEMBL21027556 | 0.74 | ALDH1A1 (0.44) | ALDH1A1GAAPKMMEN1KMT2A | |
| SCHEMBL14498510 | 0.72 | TSHR (0.45) | ALDH1A1GAAMEN1KMT2AKDM4E | |
| SCHEMBL4714240 | 0.72 | TSHR (0.51) | ALDH1A1GAAPKMMEN1KMT2A | |
| SCHEMBL14498499 | 0.72 | ALDH1A1 (0.45) | ALDH1A1GAAPKMMEN1KMT2A | |
| SCHEMBL6740743 | 0.72 | PER2 (0.40) | ALDH1A1KMT2ARAB9ACBX7CDYL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7235566-B2 | Pyridinone derivatives for treatment of atherosclerosis | SMITHKLINE BEECHAM P.L.C. (GB) | 2007-06-26 | — | — | US | disclosed |
| US-7235566-B2 | Pyridinone derivatives for treatment of atherosclerosis | SMITHKLINE BEECHAM P.L.C. (GB) | 2007-06-26 | — | — | US | disclosed |
| US-5093364-A | 5-FLUOROANTHRANILIC FUNGICIDES | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-03-03 | — | — | US | disclosed |