SCHEMBL6740743

SCHEMBL6740743

CC(C)CCn1c(=O)oc(=O)c2ccc(F)cc21

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PER2 O15055 8/20 0.40
CRY1 Q16526 8/20 0.40
CRY2 Q49AN0 8/20 0.40
ALDH1A1 P00352 2/20 0.40
CD74 P04233 1/20 0.39
MIF P14174 1/20 0.39
IDO1 P14902 2/20 0.39
MET P08581 2/20 0.39
ATM Q13315 1/20 0.38
NPC1 O15118 1/20 0.36
LMNA P02545 1/20 0.36
HPGD P15428 1/20 0.36
TSHR P16473 1/20 0.36
RAB9A P51151 1/20 0.36
CBX7 O95931 1/20 0.36
CDYL2 Q8N8U2 1/20 0.36
CDYL Q9Y232 1/20 0.36
CDY1; CDY1B Q9Y6F8 1/20 0.36
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3923954 0.89 PER2 (0.40) PER2CRY1CRY2ALDH1A1
SCHEMBL6735466 0.83 ALDH1A1 (0.39) ALDH1A1NPC1LMNAHPGDTSHR
SCHEMBL5308775 0.80 ALDH1A1 (0.55) ALDH1A1LMNAHPGDTSHRKMT2A
SCHEMBL15424910 0.78 CD74 (0.39) CD74MIFIDO1METATM
SCHEMBL6236333 0.77 L3MBTL1 (0.44) ALDH1A1MIFNPC1LMNATSHR
SCHEMBL9372564 0.76 ATM (0.53) ALDH1A1CD74MIFIDO1MET
SCHEMBL9744272 0.76 ALDH1A1 (0.43) PER2CRY1CRY2ALDH1A1IDO1
SCHEMBL6232591 0.76 NOS3 (0.41) ALDH1A1IDO1LMNAHPGDKMT2A
SCHEMBL6738246 0.76 ALDH1A1 (0.40) ALDH1A1LMNAHPGDKMT2A
SCHEMBL6234062 0.76 DNM1 (0.40) ALDH1A1NPC1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040147739-A1 Novel anti-infectives SMITHKLINE BEECHAM CORPORATION 2004-07-29 US claimed
US-20040147739-A1 Novel anti-infectives SMITHKLINE BEECHAM CORPORATION 2004-07-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040147739-A1 Novel anti-infectives RPL5, RPL7, RPL35 PER2 3652/4885CRY1 4491/4885CRY2 3792/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.