Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MPL | P40238 | 3/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31295797 | 1.00 | KIF11 (0.37) | KIF11POLBGLAGAATSHR | |
| SCHEMBL30574195 | 0.83 | KIF11 (0.37) | KIF11POLBGLAGAATSHR | |
| SCHEMBL6834930 | 0.82 | P2RX7 (0.37) | KIF11POLBGLAGAATSHR | |
| SCHEMBL922455 | 0.79 | KIF11 (0.41) | KIF11POLBGLAGAATSHR | |
| SCHEMBL3336349 | 0.77 | NOTUM (0.39) | PDE2AP2RX7EPAS1IDO1HTR3E | |
| SCHEMBL8159986 | 0.77 | EPAS1 (0.36) | KIF11PDE2AP2RX7EPAS1KDM1A | |
| SCHEMBL438369 | 0.77 | KIF11 (0.39) | KIF11POLBGLAGAATSHR | |
| SCHEMBL30524328 | 0.77 | EPAS1 (0.36) | KIF11PDE2AP2RX7EPAS1KDM1A | |
| SCHEMBL10696453 | 0.74 | CSNK2A2 (0.44) | KIF11TSHRPDE2AP2RX7HTR3E | |
| SCHEMBL31561613 | 0.74 | CSNK2A2 (0.44) | KIF11TSHRPDE2AP2RX7HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5082971-A | TRIFLUOROMETHYLAMINOBENZENES CONTAINING FLUORINE AND/OR CHLORINE AND THEIR PREPARATION | BAYER AKTIENGESELLSCHAFT (DE) | 1992-01-21 | — | — | US | claimed |
| US-5082971-A | TRIFLUOROMETHYLAMINOBENZENES CONTAINING FLUORINE AND/OR CHLORINE AND THEIR PREPARATION | BAYER AKTIENGESELLSCHAFT (DE) | 1992-01-21 | — | — | US | disclosed |
| US-4963181-A | Fungicidal 3-cyano-4-phenyl-pyrrole derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-16 | — | — | US | disclosed |
| US-4952601-A | Fungicidal 3-cyano-4-phenyl-pyrrole derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1990-08-28 | — | — | US | disclosed |
| EP-0339422-A1 | 3-Cyano-4-phenyl-pyrrole derivatives | BAYER AG (DE) | 1989-11-02 | — | — | EP | disclosed |
| EP-0315869-A2 | 3-Cyano-4-(2,4-difluor-3-phenyl)-pyrrole | BAYER AG (DE) | 1989-05-17 | — | — | EP | disclosed |
| EP-0315863-A2 | Trifluoromethylamino benzenes containing fluorine, and their preparation | BAYER AG (DE) | 1989-05-17 | — | — | EP | disclosed |