SCHEMBL9747740

SCHEMBL9747740

C=C(C)C(=O)OCCN(CCN(CC)CC)C(N)=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.44
TSHR P16473 5/20 0.42
CYP2D6 P10635 2/20 0.36
MAOA P21397 2/20 0.36
HTR3A P46098 2/20 0.36
HRH3 Q9Y5N1 2/20 0.36
BLM P54132 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
CHRM2 P08172 5/20 0.35
CHRM3 P20309 4/20 0.35
CHRM1 P11229 3/20 0.35
CHRM4 P08173 2/20 0.35
CHRM5 P08912 1/20 0.35
LMNA P02545 3/20 0.33
CYP1A2 P05177 1/20 0.33
ALDH1A1 P00352 2/20 0.33
CYP3A4 P08684 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HTR2C P28335 1/20 0.32
CHRNA4 P43681 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5360846 0.89 THRB (0.48) THRBTSHRCHRM2CHRM3CHRM1
SCHEMBL9748896 0.84 THRB (0.42) THRBTSHRCHRM2CHRM3CHRM1
SCHEMBL10444657 0.84 THRB (0.49) THRBTSHRCYP2D6MAOAHTR3A
SCHEMBL14874 0.84 THRB (0.55) THRBTSHRCYP2D6MAOAHTR3A
SCHEMBL28273630 0.84 THRB (0.55) THRBTSHRCYP2D6MAOAHTR3A
SCHEMBL9324299 0.83 THRB (0.43) THRBTSHRALDH1A1POLB
SCHEMBL28477901 0.82 THRB (0.50) THRBTSHRCYP2D6MAOAHTR3A
SCHEMBL22684899 0.82 THRB (0.53) THRBTSHRCYP2D6MAOAHTR3A
Hydrochloric Acid SCHEMBL2847352 0.82 THRB (0.53) THRBTSHRCYP2D6MAOAHTR3A
SCHEMBL9800939 0.82 THRB (0.53) THRBTSHRCYP2D6MAOAHTR3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0199306-B1 WASH-OFF FILM CONTAINING SYNTHETIC AMPHOTERIC POLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-03-11 EP disclosed
US-4735887-A ACRYLIC MONOMERS COMPRISING A CARBOXYLIC ACID, PRIM-AMINOALKYL ACRYLATE AND SEC OR TERT-AMINOALKYL ACRYLATE; GELATIN REPLACEMENT IN PHOTOGRAPHIC LAYERS; RESOLUTION E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-04-05 US disclosed
EP-0199306-A2 Wash-off film containing synthetic amphoteric polymers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-10-29 EP disclosed