Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9747967 | 1.00 | APP (0.62) | APPHTTGAAMAPTBCHE | |
| SCHEMBL9208663 | 0.82 | HTT (0.74) | APPHTTGAAMAPTBCHE | |
| SCHEMBL8473136 | 0.81 | HTT (0.69) | HTTGAAMAPTBCHEACHE | |
| SCHEMBL8472225 | 0.80 | HTT (0.71) | HTTGAAMAPTBCHEACHE | |
| SCHEMBL8476129 | 0.79 | HTT (0.73) | HTTGAAMAPTBCHEACHE | |
| SCHEMBL7945036 | 0.78 | BCHE (0.65) | APPBCHEACHE | |
| SCHEMBL8474173 | 0.78 | BCHE (0.66) | APPHTTGAAMAPTBCHE | |
| SCHEMBL28333375 | 0.77 | ACHE (0.70) | BCHEACHE | |
| SCHEMBL28333377 | 0.77 | ACHE (0.70) | BCHEACHE | |
| SCHEMBL9382159 | 0.77 | KDM4E (0.65) | APPHTTGAAMAPTBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175172-A | Administering amino-1,2,3,4-tetrahydroacridine and derivatives for elevation of T4 lymphocytes level in patients | DIETLIN FRANCOIS (FR) | 1992-12-29 | — | — | US | disclosed |