Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HGFAC | Q04756 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9748423 | 0.93 | MIF (0.53) | HSD17B10P2RY6MIFCA1CA2 | |
| SCHEMBL1421354 | 0.85 | RAB9A (0.56) | CA1CA2PRSS1MAPTCASP3 | |
| SCHEMBL941258 | 0.81 | P2RY6 (0.50) | HSD17B10P2RY6MIFCA1CA2 | |
| SCHEMBL13496888 | 0.80 | HSD17B10 (0.44) | HSD17B10P2RY6MIFCA1CA2 | |
| SCHEMBL13496887 | 0.80 | HSD17B10 (0.44) | HSD17B10P2RY6MIFCA1CA2 | |
| SCHEMBL2590530 | 0.80 | CA1 (0.45) | HSD17B10P2RY6MIFCA1CA2 | |
| SCHEMBL1457515 | 0.80 | MAPT (0.56) | CA1CA2PRSS1MAPTRAB9A | |
| SCHEMBL8511816 | 0.80 | HSD17B10 (0.38) | HSD17B10P2RY6MIFCA1CA2 | |
| SCHEMBL23481284 | 0.79 | HSD17B10 (0.49) | HSD17B10P2RY6MIFCA1CA2 | |
| SCHEMBL455561 | 0.79 | MIF (0.54) | HSD17B10P2RY6MIFCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220899-B1 | BIFUNCTIONAL LINKER | Immunomedics, Inc. (US) | 1992-03-11 | — | — | EP | disclosed |
| US-4680338-A | Bifunctional linker | IMMUNOMEDICS, INC. (US) | 1987-07-14 | — | — | US | disclosed |