Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | CASP3 | P42574 | 2/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | ACR | P10323 | 1/20 | 0.41 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.41 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9748412 | 0.93 | HSD17B10 (0.46) | MIFHSD17B10MAPTRAB9ACASP3 | |
| SCHEMBL635606 | 0.84 | MIF (0.59) | MIFHSD17B10MAPTRAB9AL3MBTL1 | |
| SCHEMBL8717537 | 0.79 | LMNA (0.67) | HSD17B10MAPTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL1421354 | 0.79 | RAB9A (0.56) | MAPTRAB9ACASP3SENP7SENP6 | |
| SCHEMBL455561 | 0.77 | MIF (0.54) | MIFHSD17B10ALDH1A1KMT2ATSHR | |
| SCHEMBL6755096 | 0.77 | PRSS1 (0.53) | HSD17B10F2PARP10PRSS1ACR | |
| Benzene SCHEMBL27793442 | 0.77 | LMNA (0.70) | HSD17B10MAPTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL52413 | 0.77 | LMNA (0.70) | HSD17B10MAPTL3MBTL1ALDH1A1KMT2A | |
| Hydrogen Peroxide SCHEMBL27952375 | 0.77 | LMNA (0.70) | HSD17B10MAPTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL27517752 | 0.76 | MIF (0.52) | MIFHSD17B10ALDH1A1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220899-B1 | BIFUNCTIONAL LINKER | Immunomedics, Inc. (US) | 1992-03-11 | — | — | EP | disclosed |
| US-4680338-A | Bifunctional linker | IMMUNOMEDICS, INC. (US) | 1987-07-14 | — | — | US | disclosed |