Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 14/20 | 0.83 |
| ▸ | MAPK12 | P53778 | 14/20 | 0.83 |
| ▸ | MAPK11 | Q15759 | 14/20 | 0.83 |
| ▸ | MAPK14 | Q16539 | 14/20 | 0.83 |
| ▸ | GCGR | P47871 | 12/20 | 0.83 |
| ▸ | RAF1 | P04049 | 4/20 | 0.73 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.60 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.57 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.57 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.57 |
| ▸ | FRK | P42685 | 1/20 | 0.57 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.57 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.57 |
| ▸ | GSK3B | P49841 | 1/20 | 0.57 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.57 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.57 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.57 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3956357 | 0.94 | MAPK13 (0.74) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL2127491 | 0.93 | MAPK13 (0.85) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL6469052 | 0.91 | MAPK13 (0.73) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL2649730 | 0.91 | MAPK13 (1.00) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL6471005 | 0.91 | MAPK13 (1.00) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL29587593 | 0.91 | CYP19A1 (0.72) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL6464698 | 0.87 | NOX1 (0.74) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL5921859 | 0.86 | MAPK13 (1.00) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL6469111 | 0.86 | MAPK13 (1.00) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL6469126 | 0.84 | MAPK13 (1.00) | MAPK13MAPK12MAPK11MAPK14GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11963948-B1 | 2-(4-chlorophenyl)-4,5-bis(4-chlorophenyl)-1H-imidazole as an antimicrobial compound | King Faisal University (SA) | 2024-04-23 | — | — | US | claimed |
| US-11963948-B1 | 2-(4-chlorophenyl)-4,5-bis(4-chlorophenyl)-1H-imidazole as an antimicrobial compound | King Faisal University (SA) | 2024-04-23 | — | — | US | disclosed |
| US-11963948-B1 | 2-(4-chlorophenyl)-4,5-bis(4-chlorophenyl)-1H-imidazole as an antimicrobial compound | King Faisal University (SA) | 2024-04-23 | — | — | US | disclosed |
| US-11963948-B1 | 2-(4-chlorophenyl)-4,5-bis(4-chlorophenyl)-1H-imidazole as an antimicrobial compound | King Faisal University (SA) | 2024-04-23 | — | — | US | disclosed |
| EP-0236628-B1 | INHIBITION OF THE 5-LIPOXYGENASE PATHWAY | SMITHKLINE BEECHAM CORPORATION (US) | 1992-12-02 | — | — | EP | disclosed |
| US-4780470-A | WITH 4,5-DIALKYL-2(SUBSTITUTED)IMIDAZOLE | SMITHKLINE BECKMAN CORPORATION (US) | 1988-10-25 | — | — | US | disclosed |
| EP-0236628-A1 | Inhibition of the 5-lipoxygenase pathway | SMITHKLINE BEECHAM CORPORATION (US) | 1987-09-16 | — | — | EP | disclosed |
| US-4686231-A | 4,5-DIARYL-2-SUBSTITUTED-IMIDAZOLE | SMITHKLINE BECKMAN CORPORATION (US) | 1987-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11963948-B1 | 2-(4-chlorophenyl)-4,5-bis(4-chlorophenyl)-1H-imidazole as an antimicrobial compound | IL4, CASP4, TLR4 | MAPK13 1792/4885MAPK12 1593/4885MAPK11 2082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.