Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
| ▸ | PYGM | P11217 | 1/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10677516 | 0.87 | LMNA (0.44) | RAB9AALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL9830525 | 0.87 | RAB9A (0.49) | RAB9AALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL10674390 | 0.85 | LMNA (0.43) | RAB9AALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL7288638 | 0.83 | PDPK1 (0.44) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL7291385 | 0.82 | CYP3A4 (0.40) | ALDH1A1KDM4EMAPTLMNAMEN1 | |
| SCHEMBL9748247 | 0.79 | RAB9A (0.40) | RAB9AMAPTLMNACACNA1SCYP3A4 | |
| SCHEMBL7288930 | 0.78 | RAB9A (0.39) | RAB9AMAPTLMNACACNA1SCYP3A4 | |
| SCHEMBL9749448 | 0.77 | RAB9A (0.39) | RAB9AALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL7278811 | 0.77 | PTPN1 (0.41) | RAB9AALDH1A1MAPTPKMLMNA | |
| SCHEMBL7282106 | 0.75 | SLC2A1 (0.47) | RAB9AALDH1A1KDM4ENPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0237573-B1 | NOVEL BENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1992-01-15 | — | — | EP | disclosed |
| US-4786635-A | THERAPEUTIC AGENTS FOR CIRCULATORY DISEASES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1988-11-22 | — | — | US | disclosed |
| EP-0237573-A1 | NOVEL BENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1987-09-23 | — | — | EP | disclosed |
| US-4584300-A | Platelet anti-aggregative- and calcium antagonistic -1,4-benzothiazin-3-one derivatives, compositions, and methods of use therefor | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1986-04-22 | — | — | US | disclosed |