Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TOP1 | P11387 | 3/20 | 0.44 |
| ▸ | CYCS | P99999 | 4/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9587290 | 0.93 | MEN1 (0.57) | MEN1KMT2ATOP1CYCSABCG2 | |
| SCHEMBL10730297 | 0.84 | MEN1 (0.57) | MEN1KMT2ATOP1CYCSABCG2 | |
| SCHEMBL29558419 | 0.83 | TOP1 (0.61) | MEN1KMT2ATOP1CYCSABCG2 | |
| SCHEMBL3794157 | 0.83 | TOP1 (0.61) | MEN1KMT2ATOP1CYCSABCG2 | |
| Acetoacetic Acid SCHEMBL9748613 | 0.78 | STAT3 (0.48) | TOP1CYCSABCG2HPGDMETAP1 | |
| SCHEMBL25395411 | 0.76 | TOP1 (0.51) | TOP1CYCSENPP2TERTSMN1; SMN2 | |
| SCHEMBL14080379 | 0.76 | TOP1 (0.51) | TOP1CYCSENPP2TERTSMN1; SMN2 | |
| SCHEMBL2173908 | 0.76 | TOP1 (0.51) | TOP1CYCSENPP2TERTSMN1; SMN2 | |
| SCHEMBL14080609 | 0.76 | TOP1 (0.51) | TOP1CYCSENPP2TERTSMN1; SMN2 | |
| SCHEMBL10726864 | 0.75 | ENPP2 (0.69) | MEN1KMT2ATOP1CYCSABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991010667-A1 | PORPHYRIN DERIVATIVES AND METALLOPORPHYRINS OPTIONALLY COUPLED WITH A BIOLOGICALLY ACTIVE MOLECULE, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | CIS BIO INTERNATIONAL (FR) | 1991-07-25 | — | — | WO | disclosed |