SCHEMBL9748680

SCHEMBL9748680

Cc1cccc(CCC(O)C(C)C)c1

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.52
HRH3 Q9Y5N1 1/20 0.44
ACHE P22303 1/20 0.43
MEN1 O00255 1/20 0.43
MAPT P10636 1/20 0.43
KMT2A Q03164 1/20 0.43
GAA P10253 1/20 0.43
ALOX12 P18054 1/20 0.43
HTT P42858 1/20 0.43
DAO P14920 2/20 0.42
IDO1 P14902 2/20 0.42
GPR84 Q9NQS5 1/20 0.41
TSHR P16473 1/20 0.40
ALDH1A1 P00352 1/20 0.40
CYP2D6 P10635 1/20 0.40
XIAP P98170 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10409369 0.85 TAAR1 (0.55) TAAR1HRH3MEN1MAPTKMT2A
SCHEMBL9748685 0.82 TAAR1 (0.52) TAAR1HRH3MEN1MAPTKMT2A
SCHEMBL28362181 0.81 ACHE (0.46) TAAR1HRH3ACHEIDO1TSHR
SCHEMBL3056983 0.81 TAAR1 (0.59) TAAR1HRH3ACHEMEN1MAPT
SCHEMBL23530305 0.80 TAAR1 (0.53) TAAR1HRH3ACHEMEN1MAPT
SCHEMBL10235710 0.79 LPL (0.45) HTTXIAP
SCHEMBL108917 0.79 TRPA1 (0.50) MEN1KMT2AHTTTSHRCYP2D6
SCHEMBL3631399 0.79 TAAR1 (0.52) TAAR1HRH3MEN1MAPTKMT2A
SCHEMBL5477927 0.78 TAAR1 (0.56) TAAR1HRH3IDO1CYP2D6
SCHEMBL612474 0.78 TAAR1 (0.40) TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0217159-B1 ALDEHYDES, ACETALS, ALCOHOLS AND ETHERS WITH 3-METHYL OR 3,5-DIMETHYLBENZYL GROUPS, THEIR PREPARATION AND THEIR USE AS FRAGRANCE COMPOUNDS Consortium für elektrochemische Industrie GmbH (DE) 1992-01-02 EP disclosed
US-4710316-A Aldehydes, acetals, alcohols and ethers having 3-methyl- or 3,5-dimethyl-benzyl groups, their manufacture and perfume materials containing same CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1987-12-01 US disclosed
EP-0217159-A2 Aldehydes, acetals, alcohols and ethers with 3-methyl or 3,5-dimethylbenzyl groups, their preparation and their use as fragrance compounds Consortium für elektrochemische Industrie GmbH (DE) 1987-04-08 EP disclosed