SCHEMBL9748773

SCHEMBL9748773

CCC=CCc1cccc(CC=CCC)c1-c1cc(C)ccc1C

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.35
S1PR4 O95977 3/20 0.33
GAA P10253 1/20 0.33
S1PR2 O95136 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
TSHR P16473 1/20 0.32
CYP2C19 P33261 1/20 0.32
MAPT P10636 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
HTT P42858 1/20 0.30
PDK2 Q15119 1/20 0.30
NQO1 P15559 1/20 0.30
POR P16435 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2176548 0.80 S1PR4 (0.41) TAAR1S1PR4S1PR2MAPTMEN1
SCHEMBL1879329 0.70 TAAR1 (0.48) TAAR1GAATSHRMAPTMEN1
SCHEMBL1879330 0.70 TAAR1 (0.48) TAAR1GAATSHRMAPTMEN1
SCHEMBL699897 0.69 ALDH1A1 (0.46) TAAR1S1PR4GAAS1PR2MAPT
SCHEMBL15501856 0.68 TRPA1 (0.43) GAACYP3A4TSHRMAPTSMN1; SMN2
SCHEMBL8845072 0.67 IDO1 (0.50) TAAR1
SCHEMBL10319049 0.67 KMT2A (0.34) TAAR1S1PR4GAAS1PR2CYP3A4
SCHEMBL19125208 0.67 MAPK1 (0.44) CYP3A4TSHRMAPTSMN1; SMN2MEN1
SCHEMBL9776402 0.66 ELANE (0.47) TAAR1S1PR4GAAMAPTMEN1
SCHEMBL277702 0.65 PBRM1 (0.44) S1PR4GAAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5130356-A Addition of small amounts of diphenoquinone or diphenohydroquinone derivatives; compact disc substrates BASF AKTIENGESELLSCHAFT (DE) 1992-07-14 US disclosed