SCHEMBL9748805

SCHEMBL9748805

CCNc1ccc(NCCO)c([N+](=O)[O-])c1

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.58
TSHR P16473 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
HCAR3 P49019 4/20 0.55
PKM P14618 3/20 0.52
MAPT P10636 7/20 0.50
LMNA P02545 3/20 0.49
RAB9A P51151 3/20 0.48
NPC1 O15118 1/20 0.48
CRHBP P24387 1/20 0.48
CRHR2 Q13324 1/20 0.48
POLB P06746 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
GALR3 O60755 1/20 0.47
KAT2B Q92831 2/20 0.47
KMT2A Q03164 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9776282 0.94 HCAR3 (0.58) ALDH1A1TSHRTDP1HCAR3PKM
SCHEMBL29392416 0.91 ALDH1A1 (0.68) ALDH1A1TSHRTDP1HCAR3PKM
SCHEMBL127370 0.91 ALDH1A1 (0.68) ALDH1A1TSHRTDP1HCAR3PKM
SCHEMBL11772321 0.88 HCAR3 (0.57) ALDH1A1TSHRTDP1HCAR3PKM
SCHEMBL10536086 0.87 ALDH1A1 (0.59) ALDH1A1TSHRTDP1HCAR3PKM
SCHEMBL8645124 0.86 ALDH1A1 (0.61) ALDH1A1TSHRTDP1HCAR3PKM
SCHEMBL7031913 0.86 ALDH1A1 (0.61) ALDH1A1TSHRTDP1HCAR3PKM
SCHEMBL7095920 0.84 ALDH1A1 (0.60) ALDH1A1TSHRTDP1PKMMAPT
SCHEMBL19666254 0.84 ALDH1A1 (0.54) ALDH1A1TSHRTDP1HCAR3PKM
SCHEMBL9776301 0.84 HTT (0.61) ALDH1A1TSHRTDP1HCAR3PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4900869-A Process for the production of 4-[ethyl-(2'-hydroxyethyl)-amino]-1-[(2'-hydroxyethyl)-amino]-2-nitrobenzene Wella, Aktiengesellschaft (DE) 1990-02-13 US claimed
US-5132461-A Process for the production of 4-[ethyl-(2'-hydroxyethyl)-amino]-1-[(2'-hydroxyethyl)-amino]-2-nitro-benzene WELLA AKTIENGESELLSCHAFT (DE) 1992-07-21 US disclosed
US-5132461-A Process for the production of 4-[ethyl-(2'-hydroxyethyl)-amino]-1-[(2'-hydroxyethyl)-amino]-2-nitro-benzene WELLA AKTIENGESELLSCHAFT (DE) 1992-07-21 US disclosed
US-4900869-A Process for the production of 4-[ethyl-(2'-hydroxyethyl)-amino]-1-[(2'-hydroxyethyl)-amino]-2-nitrobenzene Wella, Aktiengesellschaft (DE) 1990-02-13 US disclosed
US-4900869-A Process for the production of 4-[ethyl-(2'-hydroxyethyl)-amino]-1-[(2'-hydroxyethyl)-amino]-2-nitrobenzene Wella, Aktiengesellschaft (DE) 1990-02-13 US disclosed
US-3930792-A NITROAMINOBENZENE, QUATERNARY AMINE, N-OXYALKYLATED FATTY ACID AMIDES CLAIROL INCORPORATED (US) 1976-01-06 US disclosed