Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | ACHE | P22303 | 4/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8476129 | 0.89 | HTT (0.73) | HTTGAAKMT2AMAPTACHE | |
| SCHEMBL10061487 | 0.87 | HTT (0.67) | HTTGAAKMT2AMAPTACHE | |
| SCHEMBL27961246 | 0.83 | ACHE (0.70) | ACHEBCHE | |
| SCHEMBL27961244 | 0.81 | ACHE (0.68) | ACHEBCHE | |
| SCHEMBL9208663 | 0.80 | HTT (0.74) | HTTGAAMAPTACHEBCHE | |
| SCHEMBL8473136 | 0.79 | HTT (0.69) | HTTGAAMAPTACHEHDAC6 | |
| SCHEMBL8472225 | 0.78 | HTT (0.71) | HTTGAAMAPTACHEBCHE | |
| SCHEMBL3798774 | 0.78 | HTT (0.55) | HTTGAAMAPTACHEBCHE | |
| SCHEMBL9747579 | 0.76 | BCHE (0.83) | HTTGAAKMT2AMAPTACHE | |
| SCHEMBL8474173 | 0.76 | BCHE (0.66) | HTTGAAMAPTACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175172-A | Administering amino-1,2,3,4-tetrahydroacridine and derivatives for elevation of T4 lymphocytes level in patients | DIETLIN FRANCOIS (FR) | 1992-12-29 | — | — | US | disclosed |