Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 14/20 | 0.41 |
| ▸ | CPA3 | P15088 | 1/20 | 0.39 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.35 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9749243 | 0.85 | CPA1 (0.36) | FOLH1CPA3 | |
| SCHEMBL9750233 | 0.80 | KDM4E (0.40) | — | |
| SCHEMBL9749609 | 0.73 | KDM4E (0.38) | FOLH1CPA3GRM3 | |
| SCHEMBL9814887 | 0.66 | FOLH1 (0.61) | FOLH1GRM3NAALAD2 | |
| SCHEMBL7053102 | 0.64 | CPA3 (0.63) | FOLH1CPA3NAALAD2 | |
| SCHEMBL108166 | 0.63 | FOLH1 (0.76) | FOLH1GRM3NAALAD2 | |
| SCHEMBL9558884 | 0.63 | PLA2G2A (0.49) | CPA3 | |
| SCHEMBL9645833 | 0.63 | EGFR (0.43) | FOLH1CPA3 | |
| SCHEMBL9645139 | 0.63 | CPA3 (0.42) | FOLH1CPA3 | |
| SCHEMBL7289773 | 0.62 | CPA1 (0.46) | FOLH1CPA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194572-B1 | HETEROCYCLIC SULFIDES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-02 | — | — | EP | disclosed |
| US-4762848-A | IMMUNE SYSTEM STIMULANTS, CYTOSTATIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |
| EP-0194572-A1 | Heterocyclic sulfides, process for their preparation and Medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-09-17 | — | — | EP | disclosed |