Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.39 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.39 |
| ▸ | GRIK4 | Q16099 | 2/20 | 0.39 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9749646 | 0.83 | KDM4E (0.45) | MEN1KMT2ASIRT2KDM4EMAPT | |
| SCHEMBL8617954 | 0.81 | SIRT2 (0.43) | KMT2ASIRT2MAPTALDH1A1HPGD | |
| SCHEMBL8618891 | 0.79 | GRIK1 (0.57) | SIRT2GRIK1GRIK2GRIK3GRIK4 | |
| SCHEMBL8617971 | 0.78 | SIRT2 (0.40) | KMT2ASIRT2MAPTHPGDGRIK1 | |
| SCHEMBL8619770 | 0.78 | GRIA1 (0.44) | KMT2ASIRT2MAPTHPGDGRIK1 | |
| SCHEMBL8620799 | 0.76 | SIRT2 (0.37) | MEN1KMT2ASIRT2KDM4EMAPT | |
| Bicarbonate SCHEMBL8806909 | 0.76 | SIRT2 (0.47) | KMT2ASIRT2MAPTHPGDGRIK1 | |
| SCHEMBL8624320 | 0.74 | SIRT2 (0.35) | MEN1KMT2ASIRT2MAPTALDH1A1 | |
| SCHEMBL8622359 | 0.72 | SIRT2 (0.39) | KMT2ASIRT2MAPTHPGDGRIK1 | |
| SCHEMBL8624831 | 0.72 | SIRT2 (0.40) | KMT2ASIRT2MAPTHPGDGRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511152-A2 | Quinoxaline compounds, their preparation and use | NOVO NORDISK A/S (DK) | 1992-10-28 | — | — | EP | disclosed |