Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | RORA | P35398 | 3/20 | 0.42 |
| ▸ | RORC | P51449 | 3/20 | 0.42 |
| ▸ | RORB | Q92753 | 3/20 | 0.42 |
| ▸ | PGR | P06401 | 3/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9749640 | 0.83 | MEN1 (0.43) | KDM4EMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8620601 | 0.81 | SIRT2 (0.43) | KDM4ESIRT2PARP1ALDH1A1HPGD | |
| SCHEMBL8623646 | 0.79 | GRIK1 (0.54) | SIRT2PARP1 | |
| SCHEMBL8616658 | 0.78 | SIRT2 (0.40) | MAPTMEN1KMT2AHTTSIRT2 | |
| SCHEMBL8618714 | 0.78 | GRIA1 (0.44) | MEN1KMT2ASIRT2PARP1 | |
| SCHEMBL9396447 | 0.77 | SMN1; SMN2 (0.53) | KDM4EMAPTSMN1; SMN2HSD17B10HTT | |
| SCHEMBL9395611 | 0.77 | SMN1; SMN2 (0.53) | KDM4EMAPTSMN1; SMN2HSD17B10HTT | |
| Bicarbonate SCHEMBL8807164 | 0.76 | SIRT2 (0.47) | KDM4EMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8617993 | 0.72 | SIRT2 (0.39) | KDM4EMAPTMEN1KMT2AHTT | |
| SCHEMBL9395672 | 0.72 | RORA (0.52) | KDM4ESMN1; SMN2HSD17B10SIRT2RORA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511152-A2 | Quinoxaline compounds, their preparation and use | NOVO NORDISK A/S (DK) | 1992-10-28 | — | — | EP | disclosed |