SCHEMBL9749671

SCHEMBL9749671

CC(=O)c1ccc2ccccc2c1N.Cc1cc(N)c2ccccc2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
HPGD P15428 3/20 0.44
MAPT P10636 2/20 0.44
CYP1A1 P04798 1/20 0.44
CYP1B1 Q16678 1/20 0.44
MAOB P27338 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP2A6 P11509 1/20 0.40
NCEH1 Q6PIU2 1/20 0.40
HSD17B10 Q99714 3/20 0.38
TP53 P04637 1/20 0.38
KMT2A Q03164 5/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
HPRT1 P00492 1/20 0.38
KDM4E B2RXH2 2/20 0.37
GAA P10253 2/20 0.37
WDR5 P61964 1/20 0.37
LMNA P02545 1/20 0.37
MEN1 O00255 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2831990 0.85 CYP1A1 (0.55) ALDH1A1HPGDMAPTCYP1A1CYP1B1
SCHEMBL4074691 0.78 CYP2A6 (0.61) ALDH1A1HPGDCYP1B1CYP1A2CYP2A6
Hydrochloric Acid SCHEMBL10628964 0.77 CYP2A6 (0.59) ALDH1A1HPGDCYP1B1CYP1A2CYP2A6
SCHEMBL6362640 0.75 CYP1A2 (0.53) ALDH1A1HPGDMAPTMAOBCYP1A2
SCHEMBL28995877 0.71 HSD17B10 (0.53) ALDH1A1HPGDMAPTCYP1A1CYP1B1
SCHEMBL2681512 0.71 MEN1 (0.52) ALDH1A1HPGDMAPTCYP1A1CYP1B1
SCHEMBL689752 0.70 WDR5 (0.66) ALDH1A1HPGDMAPTCYP1A1CYP1B1
SCHEMBL30791069 0.70 WDR5 (0.66) ALDH1A1HPGDMAPTCYP1A1CYP1B1
SCHEMBL8097610 0.70 CYP1A1 (0.57) ALDH1A1HPGDMAPTCYP1A1CYP1B1
SCHEMBL9618656 0.70 TSHR (0.52) ALDH1A1HPGDMAPTMAOBCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5171891-A Using sulfur containing oxy acids and their salts ALLIED-SIGNAL INC. (US) 1992-12-15 US disclosed