Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | DAGLA | Q9Y4D2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.36 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9847588 | 0.90 | ALDH1A1 (0.44) | ALDH1A1MAPK1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL9748815 | 0.78 | MMP2 (0.41) | MAPK1SMN1; SMN2DAGLAMAPTMEN1 | |
| SCHEMBL10731723 | 0.76 | ALDH1A1 (0.50) | ALDH1A1MAPK1SMN1; SMN2DAGLAMAPT | |
| SCHEMBL9847605 | 0.76 | ALDH1A1 (0.42) | ALDH1A1MAPK1PPARGPPARA | |
| SCHEMBL9847593 | 0.76 | ALDH1A1 (0.42) | ALDH1A1MAPK1SMN1; SMN2AKT1MAPT | |
| SCHEMBL10434159 | 0.76 | KDM4E (0.37) | AKT1MAPTGAAHRH3 | |
| SCHEMBL9749407 | 0.75 | AKT1 (0.51) | ALDH1A1AKT1MAPTGAA | |
| SCHEMBL9749356 | 0.74 | ALDH1A1 (0.48) | ALDH1A1MAPK1SMN1; SMN2DAGLAMAPT | |
| SCHEMBL11708131 | 0.73 | MAOB (0.50) | ALDH1A1SMN1; SMN2PPARGPPARAHRH3 | |
| SCHEMBL9847551 | 0.71 | PPARG (0.43) | ALDH1A1MAPK1SMN1; SMN2PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230475-B1 | NOVEL UREA DERIVATIVES, PROCESSES FOR PRODUCTION THEREOF AND HERBICIDE | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1992-03-18 | — | — | EP | disclosed |
| US-4838924-A | NONPHYTOTOXIC | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1989-06-13 | — | — | US | disclosed |