Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.37 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAF1 | P04049 | 4/20 | 0.37 |
| ▸ | BRAF | P15056 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | ARAF | P10398 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9847575 | 0.83 | PPARG (0.40) | PPARGPPARAMTNR1BNPC1RAB9A | |
| SCHEMBL9749678 | 0.78 | ALDH1A1 (0.44) | PPARGPPARAABHD6DAGLAPOLB | |
| SCHEMBL9847644 | 0.77 | MEN1 (0.43) | PPARGPPARAMTNR1BRAB9AMTNR1A | |
| SCHEMBL9847586 | 0.72 | PPARA (0.38) | PPARGPPARAMTNR1BNPC1RAB9A | |
| SCHEMBL9847547 | 0.72 | PPARA (0.42) | PPARGPPARAMTNR1BPOLBSMN1; SMN2 | |
| SCHEMBL9754850 | 0.70 | MTNR1B (0.38) | MTNR1BNPC1RAB9APOLBRAF1 | |
| SCHEMBL12362185 | 0.70 | ALDH1A1 (0.56) | MMP2MMP9MMP14MTNR1BNPC1 | |
| SCHEMBL9749407 | 0.70 | AKT1 (0.51) | MAPT | |
| SCHEMBL9847608 | 0.69 | MTNR1B (0.39) | MTNR1BNPC1RAB9ARAF1EPHX2 | |
| SCHEMBL9847588 | 0.69 | ALDH1A1 (0.44) | PPARGPPARAPOLBMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230475-B1 | NOVEL UREA DERIVATIVES, PROCESSES FOR PRODUCTION THEREOF AND HERBICIDE | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1992-03-18 | — | — | EP | disclosed |
| US-4838924-A | NONPHYTOTOXIC | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1989-06-13 | — | — | US | disclosed |