Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ATM | Q13315 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9749407 | 0.83 | AKT1 (0.51) | KDM4ECOXFA4AKT1RXRAMAPT | |
| SCHEMBL6849624 | 0.80 | PKM (0.49) | COXFA4AKT1PKMNPC1MAPT | |
| SCHEMBL10527939 | 0.78 | SIGMAR1 (0.41) | OPRM1 | |
| SCHEMBL14449323 | 0.77 | AKT1 (0.36) | KDM4EATMHTTCOXFA4AKT1 | |
| SCHEMBL9749678 | 0.76 | ALDH1A1 (0.44) | AKT1MAPTGAAHRH3 | |
| SCHEMBL9386634 | 0.75 | HSD11B1 (0.34) | KDM4EATMHTTCOXFA4RXRA | |
| SCHEMBL14449820 | 0.75 | KDM4E (0.36) | KDM4EATMHTTAKT1PKM | |
| SCHEMBL25513495 | 0.74 | AKT1 (0.46) | KDM4EATMHTTCOXFA4AKT1 | |
| SCHEMBL15280340 | 0.73 | PKM (0.41) | KDM4EATMHTTCOXFA4PKM | |
| SCHEMBL9748973 | 0.73 | ALDH1A1 (0.41) | KDM4EAKT1MAPTOPRM1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354681-A2 | Ultraviolet radiation absorbing naphthalenylidene compositions | ICI AMERICAS INC. (US) | 1990-02-14 | — | — | EP | disclosed |
| US-4889947-A | SUNSCREEN LOTION | ICI AMERICAS INC. (US) | 1989-12-26 | — | — | US | disclosed |