SCHEMBL9750015

SCHEMBL9750015

O=C(OCc1ccccc1Cl)c1cc(O)c(O)c(O)c1

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.58
L3MBTL1 Q9Y468 2/20 0.56
MAPT P10636 3/20 0.56
RAB9A P51151 2/20 0.56
NPC1 O15118 1/20 0.53
SERPINE1 P05121 4/20 0.53
CASP3 P42574 1/20 0.51
SENP8 Q96LD8 1/20 0.51
SENP7 Q9BQF6 1/20 0.51
SENP6 Q9GZR1 1/20 0.51
MMP1 P03956 1/20 0.51
MMP2 P08253 1/20 0.51
MMP9 P14780 1/20 0.51
MMP12 P39900 1/20 0.51
TDP1 Q9NUW8 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9750057 0.87 RAB9A (0.58) L3MBTL1MAPTRAB9ANPC1CASP3
SCHEMBL4734719 0.86 TYR (0.72) TYRL3MBTL1SERPINE1
SCHEMBL9750049 0.84 L3MBTL1 (0.66) TYRL3MBTL1SERPINE1TDP1
SCHEMBL831262 0.83 MAPT (0.68) L3MBTL1MAPTRAB9ANPC1CASP3
SCHEMBL5421974 0.82 L3MBTL1 (0.72) L3MBTL1MAPTRAB9ANPC1CASP3
SCHEMBL9749966 0.79 TYR (0.56) TYRL3MBTL1SERPINE1
SCHEMBL4735009 0.79 TYR (0.56) TYRL3MBTL1SERPINE1TDP1
SCHEMBL14129928 0.79 MAPT (0.63) L3MBTL1MAPTRAB9ANPC1CASP3
SCHEMBL10719292 0.78 TYR (0.55) TYRL3MBTL1SERPINE1
SCHEMBL27600762 0.78 CASP3 (0.69) L3MBTL1MAPTRAB9ANPC1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5084593-A Cyanine, aniline dyes for heat sensitive recording elements RICOH COMPANY, LTD. (JP) 1992-01-28 US disclosed
US-5008238-A Thermosensitive material with phenolic developer RICOH COMPANY, LTD. (JP) 1991-04-16 US disclosed