Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750086 | 0.91 | ALDH1A1 (0.42) | MAPTRAB9ANPC1SMN1; SMN2GAA | |
| SCHEMBL9749957 | 0.85 | HDAC3 (0.40) | MAPTLMNAALDH1A1HPGDHTT | |
| SCHEMBL9750171 | 0.83 | MAPT (0.41) | MAPTCYP1A2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9750077 | 0.80 | MAPT (0.53) | MAPTCYP1A2MAOBRAB9ANPC1 | |
| SCHEMBL9750389 | 0.75 | MAOB (0.50) | MAPTCYP1A2MAOBRAB9ANPC1 | |
| SCHEMBL9750108 | 0.72 | MAOB (0.47) | MAPTCYP1A2MAOBRAB9ANPC1 | |
| SCHEMBL9839720 | 0.71 | EGFR (0.39) | MAPTTP53NOX1GAALMNA | |
| SCHEMBL10473228 | 0.71 | MAOB (0.56) | MAPTCYP1A2MAOBRAB9ANPC1 | |
| SCHEMBL10473229 | 0.71 | MAOB (0.56) | MAPTCYP1A2MAOBRAB9ANPC1 | |
| SCHEMBL9749600 | 0.70 | RAB9A (0.53) | MAPTRAB9ANPC1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084593-A | Cyanine, aniline dyes for heat sensitive recording elements | RICOH COMPANY, LTD. (JP) | 1992-01-28 | — | — | US | disclosed |
| US-5008238-A | Thermosensitive material with phenolic developer | RICOH COMPANY, LTD. (JP) | 1991-04-16 | — | — | US | disclosed |