Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750086 | 0.84 | ALDH1A1 (0.42) | MAPTHTTRAB9ANPC1ALDH1A1 | |
| SCHEMBL9750072 | 0.83 | MAPT (0.47) | MAPTLMNAHTTRAB9ANPC1 | |
| SCHEMBL9750173 | 0.82 | MAPT (0.46) | MAPTLMNAHTTNPSR1RAB9A | |
| SCHEMBL7601515 | 0.71 | MAPT (0.69) | MAPTLMNAHTTNPSR1RAB9A | |
| SCHEMBL9749600 | 0.69 | RAB9A (0.53) | MAPTLMNAHTTNPSR1RAB9A | |
| SCHEMBL9750427 | 0.68 | MAPT (0.42) | MAPTLMNAHTTNPSR1RAB9A | |
| SCHEMBL9839720 | 0.67 | EGFR (0.39) | MAPTLMNAALDH1A1TP53KMT2A | |
| SCHEMBL22074243 | 0.67 | L3MBTL1 (0.48) | MAPTLMNAHTTNPSR1RAB9A | |
| SCHEMBL29500532 | 0.67 | L3MBTL1 (0.48) | MAPTLMNAHTTNPSR1RAB9A | |
| SCHEMBL9750077 | 0.66 | MAPT (0.53) | MAPTLMNARAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084593-A | Cyanine, aniline dyes for heat sensitive recording elements | RICOH COMPANY, LTD. (JP) | 1992-01-28 | — | — | US | disclosed |