SCHEMBL9750079

SCHEMBL9750079

O=S(=O)(c1cc(Cl)c(O)cc1Cl)c1cc(Cl)c(O)cc1Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.52
HSD17B10 Q99714 4/20 0.52
HPGD P15428 2/20 0.52
ALDH1A1 P00352 3/20 0.41
CYP3A4 P08684 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
CA1 P00915 6/20 0.41
CA2 P00918 6/20 0.41
CA12 O43570 4/20 0.39
CA4 P22748 4/20 0.39
CA6 P23280 4/20 0.39
CA5A P35218 4/20 0.39
CA7 P43166 4/20 0.39
CA9 Q16790 4/20 0.39
CA14 Q9ULX7 4/20 0.39
CA5B Q9Y2D0 4/20 0.39
CA3 P07451 3/20 0.39
CA13 Q8N1Q1 3/20 0.38
CISD1 Q9NZ45 1/20 0.38
ACLY P53396 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9566720 0.88 HSD17B10 (0.50) TSHRHSD17B10HPGDALDH1A1CYP3A4
SCHEMBL10813290 0.86 HSD17B10 (0.48) TSHRHSD17B10HPGDALDH1A1CYP3A4
SCHEMBL2115165 0.86 TSHR (0.46) TSHRHSD17B10HPGDALDH1A1CYP3A4
SCHEMBL5635695 0.84 TSHR (0.50) TSHRHSD17B10HPGDALDH1A1CYP3A4
SCHEMBL10813287 0.80 TSHR (0.46) TSHRHSD17B10HPGDALDH1A1CYP3A4
SCHEMBL11859802 0.79 L3MBTL1 (0.47) TSHRHSD17B10HPGDALDH1A1CA1
SCHEMBL9566724 0.79 HSD17B10 (0.50) TSHRHSD17B10HPGDALDH1A1CYP3A4
SCHEMBL9698646 0.76 CA1 (0.55) TSHRHSD17B10HPGDTDP1CA1
SCHEMBL10788273 0.76 HSD11B1 (0.46) TSHRHSD17B10HPGDALDH1A1TDP1
SCHEMBL48305 0.76 HSD17B10 (0.86) TSHRHSD17B10HPGDALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4880767-A COLOR FORMING SYSTEMS, FLUORENE DYES, DYE DEVELOPERS MITSUBISHI PAPER MILLS (JP) 1989-11-14 US claimed
US-5084593-A Cyanine, aniline dyes for heat sensitive recording elements RICOH COMPANY, LTD. (JP) 1992-01-28 US disclosed
US-5008238-A Thermosensitive material with phenolic developer RICOH COMPANY, LTD. (JP) 1991-04-16 US disclosed
US-4983569-A Color-forming layer comprising a fluorene dye chromogen, a developer, an isocyanate and an imino compound; infrared absorption; storage stability; colorfastness MITSUBISHI PAPER MILLS (JP) 1991-01-08 US disclosed
US-4880767-A COLOR FORMING SYSTEMS, FLUORENE DYES, DYE DEVELOPERS MITSUBISHI PAPER MILLS (JP) 1989-11-14 US disclosed